Pulsatile drug delivery, circadian rhythms, Tiotropium Bromide, Lag time, Press coated tablets.
نویسندگان
چکیده
منابع مشابه
Formulation and evaluation of press coated tablets for pulsatile drug delivery using hydrophilic and hydrophobic polymers.
The aim of present investigation was to develop press coated tablet for pulsatile drug delivery of ketoprofen using hydrophilic and hydrophobic polymers. The drug delivery system was designed to deliver the drug at such a time when it could be most needful to patient of rheumatoid arthritis. The press coated tablets containing ketoprofen in the inner core was formulated with an outer shell by d...
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Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor, primarily used for the treatment of hypertension, congestive heart failure, and heart attack. It belongs to BCS class III having a half-life of 12 hrs and 25% bioavailability. The purpose of the present work was to develop a press-coated, floating-pulsatile drug delivery system. The core tablet was formulated using the super-disint...
متن کاملFormulation and Evaluation of Atenolol Pulsatile Press Coated Tablets Using Rupturable and Erodible Polymers
161 Abstract: Pulsatile systems are best for the drugs, which follows chronopharmacological behaviour where night time dosing is required, drugs having high first-pass effect and having specific site of absorption in GIT. In this study, colon targeted pulsatile release tablets of atenolol was prepared using press coating technique to treat hypertension in the early hours of the morning. Pulsati...
متن کاملTiotropium bromide
Therapy with bronchodilators forms the pharmacologic foundation of the treatment of patients with COPD. Bronchodilators can significantly lessen dyspnea, increase airflow, improve quality of life, and enhance exercise performance. While bronchodilators decrease airway resistance and lessen dynamic hyperinflation in patients with COPD, they have not been shown to alter the rate of decline in FEV...
متن کاملPulsatile Drug Delivery Systems
The ability to deliver therapeutic agents to a patient in a pulsatile or staggered release profi le has been a major goal in drug delivery research recently. This review will cover methods that have been developed to control drug delivery profi le with different polymeric systems. Externally and internally controlled systems will be considered, including a range of technologies like preprogramm...
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ژورنال
عنوان ژورنال: American Journal of PharmTech Research
سال: 2019
ISSN: 2249-3387
DOI: 10.46624/ajptr.2019.v9.i4.007